{"id":102993,"date":"2022-04-22T12:33:12","date_gmt":"2022-04-22T10:33:12","guid":{"rendered":"https:\/\/www.ivi.uk\/?p=102993"},"modified":"2024-08-22T13:07:12","modified_gmt":"2024-08-22T11:07:12","slug":"how-does-female-fertility-change-with-age","status":"publish","type":"post","link":"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/","title":{"rendered":"How does female fertility change with age?"},"content":{"rendered":"<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">You may already know that for both men and women, <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">fertility changes with age<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> &#8211; but do you understand how? <\/span><span style=\"vertical-align: inherit;\">In this article, we delve closer into female fertility specifically and how this changes with age, how age affects the chances of conceiving naturally, and some of the numbers you need to be aware of if you plan to have children in the future.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_68_1 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title \" >Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#When_it_comes_to_fertility_why_does_age_matter\" title=\"When it comes to fertility, why does age matter?\">When it comes to fertility, why does age matter?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#Does_age_affect_fertility_treatment_outcomes_too\" title=\"Does age affect fertility treatment outcomes too?\">Does age affect fertility treatment outcomes too?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#Aging_and_egg_quality\" title=\"Aging and egg quality\">Aging and egg quality<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#Ageing_and_egg_quantity\" title=\"Ageing and egg quantity\">Ageing and egg quantity<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#How_do_I_know_if_my_ovarian_reserve_is_low\" title=\"How do I know if my ovarian reserve is low?\">How do I know if my ovarian reserve is low?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/#We_are_here_to_help\" title=\"We are here to help\">We are here to help<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"When_it_comes_to_fertility_why_does_age_matter\"><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">When it comes to fertility, why does age matter?<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">From a medical perspective, getting pregnant &#8211; both naturally and through assisted conception &#8211; can be a numbers game. <\/span><span style=\"vertical-align: inherit;\">Women are born with a finite number of eggs, which gradually decreases naturally over time until the menopause is reached. <\/span><span style=\"vertical-align: inherit;\">The menopause normally coincides with your early 50s &#8211; however estimates show that by the age of 40, just 3% of egg reserve remains.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">When it comes to the aging process and female fertility, it&#8217;s important to understand two key points. <\/span><span style=\"vertical-align: inherit;\">The first is that <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">changes to fertility levels are inevitable and a natural part of aging<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">. <\/span><span style=\"vertical-align: inherit;\">They can&#8217;t be slowed down or prevented, no matter how much you exercise, take vitamins or try holistic therapies. <\/span><span style=\"vertical-align: inherit;\">However, some habits, such as smoking, can speed up the decline and put your fertility at unnecessary risk. <\/span><span style=\"vertical-align: inherit;\">The second is that <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">each woman&#8217;s optimal window of fertility is unique <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">and can vary depending on a wide range of factors. For some, fertility can begin to decline sooner than is commonly believed. <\/span><span style=\"vertical-align: inherit;\">Sometimes, as early as their 20s. <\/span><span style=\"vertical-align: inherit;\">Many women wait until their mid-30s before trying to conceive as this is when they believe they will start to experience a decline in fertility. And although many conceive without any problems, for some this decline could have begun to decline nearly a decade earlier. <\/span><span style=\"vertical-align: inherit;\">If you don&#8217;t wish to have a child right now but plan to start a family later in life, it can be beneficial to arrange a fertility assessment to inform your family-planning decisions. <\/span><span style=\"vertical-align: inherit;\">Fertility assessments are widely available, both at IVI and many other licensed fertility clinics.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">While at the age of 25, your odds of conceiving within three months of trying are high, this doesn&#8217;t mean it&#8217;s necessarily the right time to have a baby. <\/span><span style=\"vertical-align: inherit;\">In the UK, the average age of a first time mum stands at 30.7 years old. <\/span><span style=\"vertical-align: inherit;\">This figure has continued to climb gradually since 1974, when the average age was 26.4 years old. <\/span><span style=\"vertical-align: inherit;\">There are many factors which we could argue have contributed to this change. <\/span><span style=\"vertical-align: inherit;\">However, perhaps the most important thing it tells us is that <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">the right time to have a baby is when you feel you&#8217;re <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">ready:<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> whether that&#8217;s when you feel emotionally and financially stable, when your career is established, or when you meet the right partner.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">In recent years, we&#8217;ve seen a trend in the UK showing that the <a href=\"https:\/\/www.theguardian.com\/uk-news\/2016\/jul\/13\/fertility-rate-higher-over-40s-than-under-20s-first-time-since-1947\">number of women giving birth over the age of 40 to be consistently higher than the number who have a baby before the age of 20<\/a>. <\/span><span style=\"vertical-align: inherit;\">For those over 40, there may be a number of reasons for this jump &#8211; the growth in fertility treatments being one such factor. <\/span><span style=\"vertical-align: inherit;\">IVF has come on in enormous leaps and bounds in the past few decades. <\/span><span style=\"vertical-align: inherit;\">In fact, the latest data shows us that <\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">the number of babies born through IVF has tripled since 1991<\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> &#8211; and IVF birth rates continues to rise.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Does_age_affect_fertility_treatment_outcomes_too\"><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Does age affect fertility treatment outcomes too?<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">While the changes to fertility levels are well documented for those women trying to conceive naturally, less is widely known about the impact of age on your chances of successful fertility treatment. <\/span><span style=\"vertical-align: inherit;\">For women, age impacts both the quantity and the <em>quality<\/em> of eggs, which we will explain in more detail shortly. <\/span><span style=\"vertical-align: inherit;\">This means if you intend to use your own eggs in a fertility treatment, you may have a reduced chance of success depending on your age when you embark on treatment.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">The Human Fertilisation &amp; Embryology Authority (HFEA) is the UK&#8217;s regulator of fertility clinics. <\/span><span style=\"vertical-align: inherit;\">Each year, every licensed clinic is required to report its clinical activity to the HFEA, including success rates. <\/span><span style=\"vertical-align: inherit;\">By accumulating this data, the HFEA can break down the <a href=\"https:\/\/www.hfea.gov.uk\/about-us\/publications\/research-and-data\/fertility-treatment-2019-trends-and-figures\/#Section6\">national success rate for IVF<\/a> across the age ranges as follows:<\/span><\/span><\/p>\n<table>\n<tbody>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Maternal age<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Live birth rate per embryo transferred<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Under 35<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">32.3%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">35-37<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">27.7%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">38-39<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">19.2%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">40-42<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">11.9%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">43-44<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">3.4%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td width=\"622\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Over 44<\/span><\/span><\/p>\n<\/td>\n<td width=\"580\">\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">3.1%<\/span><\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p style=\"text-align: center;\">\n<span style=\"font-size: 10pt;\"><em><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Please note that these figures indicate success rates on a national scale. <\/span><span style=\"vertical-align: inherit;\">IVI London is proud to report success rates <strong>consistently above the UK national average, achieving 47% IVF success rate<\/strong> on average across all ages. <\/span><span style=\"vertical-align: inherit;\">You can <a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/success-rates\/\">view our success rates here<\/a>.<\/span><\/span><\/em><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Assisted reproductive technologies have been transformational in giving people the opportunity to start a family at a time that&#8217;s right for them. <\/span><span style=\"vertical-align: inherit;\">However, just as with natural conception, age is one of the most important considerations to take into account.<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">If you find your fertility has been compromised by age-related factors, there are other options. <\/span><span style=\"vertical-align: inherit;\">At IVI, we offer world-class <a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/egg-donation\/\">egg donation programs<\/a> in the UK and overseas. <\/span><span style=\"vertical-align: inherit;\">To take part in these programs, egg donors are carefully screened to ensure eggs are healthy and of a high enough quality to be effective when used in a fertility treatment.<\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Aging_and_egg_quality\"><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Aging and egg quality<\/span><\/span><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Normally, the ovaries release the highest quality eggs during the prime reproductive years \u2013 this normally peaks between the age of 24 and 28. Gradually, as women get older, egg quality lowers. From the age of 35 onwards, egg quality starts to decline more significantly. The problem this presents when trying to conceive is that the older an egg is, the more likely it is to develop problems during the cell division process.<\/p>\n<p>If there is a problem during the division process, it can lead to genetic abnormalities in the embryo resulting from the egg, such as aneuploidy. This occurs when fertilised eggs have too many or too few chromosomes. A healthy egg should have 23 chromosomes at the point of fertilisation, which is then matched by the sperm to give a total of 46 chromosomes. Genetic conditions such as Down\u2019s Syndrome are a result of having an abnormal number of chromosomes, such as 45 (a missing chromosome) or 47 (an extra chromosome). Importantly, there is a high chance that an embryo with too many or too few chromosomes will end in miscarriage or fail to result in pregnancy at all. This is why older women have a higher risk of miscarriage and a lower chance of pregnancy.<\/p>\n<p>At IVI, women of advanced maternal age are recommended to consider <a href=\"https:\/\/www.ivi.uk\/assisted-reproduction-treatments\/ivf-genetic-screening\/\">embryo screening<\/a> as part of their IVF treatment. This allows our scientists to collect and examine the genetic material of an embryo to establish whether it has the correct number of chromosomes and is safe to transfer. This procedure does not harm the embryo.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Ageing_and_egg_quantity\"><\/span>Ageing and egg quantity<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Women are born with all of the eggs they will ever have, each stored in a microscopic ovarian follicle. This is known as the ovarian reserve. The number of eggs is somewhere between 1 \u2013 2 million at the time of being born. This number decreases significantly during the childhood and prepubescent years while the follicles remain dormant. The natural decline continues upon reaching puberty, while eggs begin being released each month during ovulation. For the average woman with no known fertility issues, there are around 25,000 eggs remaining in the ovaries upon turning 37 years of age.<\/p>\n<p>If you are concerned about egg quantity or quality, there are ways to optimise the longevity of your eggs to some extent. It is well established that smoking tobacco can accelerate egg depletion, so quitting smoking sooner rather than later can help boost your chances of both a natural pregnancy and an assisted pregnancy. There are also lifestyle factors which can contribute to eggs being lost at a higher rate, such as stress, an unhealthy diet and the excessive intake of toxins, like those found in alcohol. Many medical professionals recommend taking steps towards a healthier lifestyle when trying to conceive with or without assistance.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_do_I_know_if_my_ovarian_reserve_is_low\"><\/span>How do I know if my ovarian reserve is low?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>There are no set rules that determine precisely how many eggs each woman has at any given time or age. On the other hand, it is possible to gain a relatively accurate estimate that can inform a woman\u2019s choice about how she wishes to proceed with family-planning. The ovarian reserve is commonly measured with a blood test to quantify the level of anti-M\u00fcllerian hormone (AMH). AMH is a hormone secreted by ovarian follicles containing eggs. The higher the measure of this hormone in your bloodstream, the higher your ovarian reserve level. We include this simple test within the <a href=\"https:\/\/www.ivi.uk\/ask-for-an-appointment\/\">IVI Diagnostic Pack<\/a>, our fertility assessment package.<\/p>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"We_are_here_to_help\"><\/span>We are here to help<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">For those concerned about the impact of aging on fertility, it can be reassuring to remember that age is no longer the barrier to having a child it used to be. <\/span><span style=\"vertical-align: inherit;\">Likewise, if you have been affected by a medical condition which has impacted your ability to have children, there are still lots of options to help you build a family. <\/span><span style=\"vertical-align: inherit;\">We work with every patient on an individual basis to deliver a tailor-made treatment journey, which carefully takes into take into account multiple factors including your age and medical history. <\/span><\/span><a href=\"https:\/\/www.ivi.uk\/ask-for-an-appointment\/\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Contact us today<\/span><\/span><\/a><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"> to find out more about how we can help you.<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"You may already know that for both men and women, fertility changes with age &#8211; but do you understand how? In this article, we delve closer into female fertility specifically and how this changes with age, how age affects the chances of conceiving naturally, and some of the numbers you need to be aware of&#8230; <a class=\"view-article\" href=\"https:\/\/www.ivi.uk\/blog\/how-does-female-fertility-change-with-age\/\">View Article<\/a>","protected":false},"author":1,"featured_media":102998,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[15],"tags":[216],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>How does female fertility change with age? - IVI UK<\/title>\n<meta name=\"description\" content=\"You may already know that for both men and women, fertility changes with age - but do you understand how? 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